Neurodegenerative相关论文
Genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain inj
Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are a recently established family of regulatory small non-coding RNAs th......
Hypoxia is a characteristic of most tumor and neurodegenerative diseases with low oxygen condition caused by numerous en......
Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and it
Neurodegenerative disease is a brain disorder caused by the loss of structure andfunction of neurons that lowers the qua......
Aging is the primary risk factor for many neurode-generative diseases.Kidney-tonifying Chinese herbs,including Liu-Wei-D......
Lipids are key regulators of brain function and have been implicated in various neurodegenerative diseases, such as ......
Baicalin influences the dendritic morphology of newborn neurons in the hippocampus of chronically st
...
Glaucoma is a chronic, progressive optic neuropathy characterized by the loss of peripheral vision first and then centra......
In the pathophysiology of neurodegenerative disorders,the role of misfolded protein deposition leading to neurodegenerat......
目的：探索腰椎穿刺鞘内注射移植间充质干细胞（MSCs）或经脑脊液诱导分化的神经样干细胞（NSCs）治疗神经变性疾病（NDD）的临床疗效和安全性。......
Glaucoma is a chronic, progressive optic neuropathy characterized by the loss of peripheral vision first and then centra......
Investigating amyloid nanofibril self-assembly, with an emphasis on the electromechanical property of amyloid peptides, ......
目的探讨TNF-α（tumor necrosis factorα,肿瘤坏死因子α）在C型Niemann-Pick病（NPC）小鼠脑部的表达及功能。方法对4周龄NPC小鼠侧脑室......
In this study,we recruited 10 neuromyelitis optica patients,two multiple sclerosis patients and two myelitis patients.Ch......
BACE1 in the retina：a sensitive biomarker for monitoring early pathological changes in Alzheimer＇s d
Because of a lack of sensitive biomarkers,the diagnosis of Alzheimer’s disease(AD) cannot be made prior to symptom mani......
Aim Adult neurogenesis is the process of generating new neurons throughout life in the olfactory bulb and hippocampus of......
Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by......
Alzheimer’s disease(AD)is a progressive neurodegenerative disease in which patients exhibit gradual loss of memory that......
Proteinaceous infectious particles(prions) are unique pathogens as they are devoid of any coding nucleic acid.Whilst it ......
Amyotrophic lateral sclerosis(ALS) is a disorder that involves the degeneration of motor neurons,muscle atrophy,and para......
Inflammation and dysregulation of immune response in Alzheimer disease, the drug target for the futu
It has been demonstrated that inflammation and dysregulation of immune response are involved in the pathogenesis of Alzh......
Characteristics and advantages of adenoassociated virus vector-mediated gene therapy for neurodegene
Common neurodegenerative diseases of the central nervous system are characterized by progressive damage to the function ......
...
Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mou
Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity and improve cognitive impai......
The emerging role of gut microbiota as a key player in the development of neurodegenerative disorders: Mammals have evol......
Tissue deposition of normally soluble proteins, or their fragments, as insoluble amyloid fibrils causes both acquired an......
Oxidative damage and redox metal homeostasis loss are two contributing factors in brain aging and widely distributed neu......
Neurodegenerative diseases are characterized by progressive degeneration and/or death of neuronal cells and results in a......
Cellular damage or oxidative injury arising from free radicals or reactive oxygen species (ROS) now appears the fun-dame......
The Prevalence of Alzheimer’s Disease and Dementia in Alzheimer’s Disease in Patients of Long-Term N
The prevalence of Alzheimer’s disease and dementia in Alzheimer’s disease according to the International Statistical C......
The brain experiences structural, molecular and functional alterations during aging. In aging brain tissue, the oxidativ......
In the past decades,single target drugs showed less therapeutic action and more side effects in treatment of complicated......
The Potential Relationship between the Incidence of Neurodegenerative Disease and Trace Mineral Comp
Many chronic degenerative diseases have been linked to high intake of various trace and heavy metals. The presence of th......
Comparative Oral Absorption of Different Citicoline and Homotaurine Formulations: A Single-Dose, Two
Background: Citicoline and homotaurine are compounds with a potent neuroprotective activity and they have been administe......
Vitamin E is one of the most important lipid-soluble antioxidants. It is essential for the neurological function but its......
The specific role of Glutamate dehydrogenase (GLDH) in the brain is not yet clear, but it is an important enzyme in prot......
Alzheimer disease(AD)is the primary form of dementia that occurs spontaneously in older adults.Interestingly,the epigene......
Our common home,planet Earth,is inhabited by more than 7 billion human beings.The average life expectancy currently esti......
Can leukocyte telomere shortening be a possible biomarker to track Huntington’s disease progression?
Huntington's disease (HD): HD is an autosomal dominant neurodegenerative disease, caused by a CAG trinucleotide repe......
Microtubules (MTs) are cytoskeletal elements formed by a non-covalent association of α- and β-tubulin heterodimers. Th......
Oxygen is essential to the human life and life of all aerobic organisms.The complete oxidation of nutrients for the biol......
Parkinson's disease (PD) is the second most common neurodegenerative disease, affecting 1% of the population over 55......
Magnetic resonance imaging in the assessment of brain involvement in alcoholic and nonalcoholic Wern
AIM To present the typical and atypical magnetic resonance(MR) imaging findings of alcoholic and non-alcoholic Wernicke......
Lycopene is a natural pigment in tomato,watermelon,pomegranate,and other plants.It belongs to the carotenoid family.It h......
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by a variable combinatio......
Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is
Patients with Parkinson's disease(PD) have impaired insulin signaling in the brain. Incretin hormones, including glu......
The treatment of neurodegenerative diseases presents a growing need for innovation in relation to recent evidence in the......
This paper elaborated the chemical components,biological metabolism,and progress in the field of drug development of gre......
Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative dis
Neurodegenerative diseases including Alzheimer’s disease,Parkinson’s disease,Huntington disease and amyotrophic latera......
Chronic exposure to low doses of ozone similar to a day of high pollution in Mexico City causes a state of oxidative str......
Nigrostriatal Degeneration in Parkinson Disease: Evaluation by Diffusion Tensor Tract-Specific Analy
Diffusion tensor tractography was used to evaluate whether diffusion metrics in the nigrostriatal pathway could diagnose......
